January 07, 2015  



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   H-I - A Homocysteine Inhibitor 


Chances Are Your Doctor Keeps Close Tabs on Your Cholesterol
But Has Never Tested Your
Homocysteine Levels?

Do you know your homocysteine (pronounced "Homo-SIS-Teen") level? No? Too bad. If we had to pick one word that could be the most important key to your cardiovascular health, that word would be "homocysteine." In recent years, scientists have discovered a risk factor for heart disease far more significant than cholesterol. This risk factor is known as homocysteine. Like cholesterol, homocysteine is a natural substance produced by the body. The problem is that many people lack the ability to break it down properly or completely.


What is homocysteine and why is it so important? homocysteine is a natural amino acid that can be toxic when it builds up to excessive levels in the body. When homocysteine is not completely broken down by the body, it becomes a very dangerous substance, causing clotting, oxidization, atherosclerosis, blocked blood flow and can injure the blood vessel wall, allowing cholesterol and other fats to infiltrate into the wall and create what is called a foam cell, thereby creating blood wall plaque. Even in moderately healthy adults, modest increases in homocysteine are associated with significantly increased risks of brain strokes, heart attacks, and arterial disease. Simply put: tracking cholesterol levels is relatively unimportant when it comes to predicting cardiovascular health and/or heart attack risk. homocysteine status is a far more realistic and important indicator.

Underscoring this conclusion is the American Heart Association's outspoken criticism of the way the homocysteine effect continues to be ignored by mainstream docs. So, chances are you know next to nothing about how homocysteine , as it reaches unhealthy levels,  promotes the buildup of plaque on blood vessel walls, increases coagulation and the danger of blood clots, and significantly multiplies your risk of heart attack and stroke.

Fortunately your homocysteine level can be easily measured with a simple blood test. And you can readily take simple steps to lower your homocysteine to a healthy level. Studies have found that your risk of heart attack and coronary artery disease begin to increase at levels of around 6.5. A homocysteine level of 10 roughly doubles your risk for CAD, and a reading of 15 (the high end of "normal") increases your risk four-fold. Readings over 15 are considered extremely dangerous.


So, what's the problem? Why the silence? Why does mainstream medicine continue to proclaim cholesterol as the primary indicator of heart disease despite ample research that shows otherwise. Why hasn't your doctor TOLD you this? Could it be because the pharmaceutical industry doesn't have a pill to treat it. If your doctor could write a prescription to lower your homocysteine - (he can't) - or if  Pfizer or Bristol-Myers Squibb or Merck made a prescription product that could reduce it, you can be sure homocysteine would be a household word.

The real explanation for the conspiracy of silence is the fact that the condition can only be corrected by appropriate nutritional supplementation. Homocysteine metabolism depends on nutrients such as folate, vitamin B6 and B12, choline and TMG which is why your homocysteine level drops when you increase your intake of these nutrients.

Homocysteine hasn't been ignored by eminent researchers. Various studies have found that persons with elevated levels in their blood are at an increased risk of heart and vessel disease.  These studies include the Physicians' Health Study, the Tromso Study from Norway, the Framingham Heart Study, and a meta-analysis of nearly 40 studies. According to a study in the European Journal of Clinical Investigation, 40% of stroke victims have elevated homocysteine compared to only 6% of controls. The study found increased homocysteine in lacunar, hemorrhagic and embolic strokes.

A study published in Lancet in 1996 showed that even after adjustment for other risk factors, homocysteine was an independent risk factor for stroke and arterial thrombosis. Another study published in Lancet came to the same conclusion after studying 107 middle-aged British men who participated in a 2-year investigation. The authors concluded that "these findings suggest that homocysteine is a strong and independent risk factor for stroke." It has even been reported that the level of homocysteine in blood correlates with the thickness of arteries. And it was reported in the Journal of Nutrition that men with levels of homocysteine above 14 mmol/L had a greater than 50% chance of stenosis in an extracranial carotid artery, whereas men with levels below 9.1 mmol/L only had a 27% incidence of stenosis. A major study involving 80,000 nurses over 14 years showed that for every 200 mcg of folate consumed daily, heart disease fell by 11%. For every 2 mg of B6, heart disease fell by 17%. Another confirming study is a Tulane University report which showed that lowering homocysteine may significantly reduce the risk of stroke and cardiovascular disease (CVD). Data from a 1992 study (published as part of the Physicians' Health Study) of  14,916 U.S. physicians with no prior history of heart disease, shows that highly elevated homocysteine levels are associated with a more than three-fold increase in the risk of heart attack over a five-year period. The Framingham Heart Study and other studies have confirmed these findings with similar data.  In 1997 the prestigious New England Journal of Medicine stated that blood levels of homocysteine was the strongest predictor of coronary heart disease and the easiest to change for the better. Later they reported that blood levels could be decreased to normal with several common B-vitamins.


And now comes additional important news: elevated homocysteine levels may double the risk of Alzheimer's, the dread disease that's afflicted ex-President Ronald Reagan and famed actor Charlton Heston. Scientists at Boston University report some of the most powerful evidence yet of an association between high plasma homocysteine and significant memory loss at some later date best described as an eight year predictor of AD. We learned long ago it's no public service to alert people to a problem without offering a solution. So, as specialists in physician recommended therapeutic nutritionals, we went right to work to develop a high quality product designed to bring relief from dangerously elevated homocysteine levels. What's more, we've managed to arrange a special low price for our customers.


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