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It is also helpful as an anti-ischemic and
cardioprotective agent in ischemic
heart disease and hypertension. Levels of triglycerides and
cholesterol have been reduced and it has been reported to
enhance the synthesis of LDL-apoprotein (apoB). It allegedly
possesses protective cardiovascular and hypolipidemic
properties. It inhibits the oxidation of LDL and accelerates the
turnover of LDL-cholesterol in liver. This increases the
expulsion of cholesterol from the body. The hepatic cholesterol
biosynthesis suppression by Terminalia arjuna is the mechanism
responsible for the recovery of HDL components in hyperlipidemia
as well as a major reduction of beta-lipoprotein lipids.
The efficacy
of the bark powder in treating congestive cardiac failure (CCF)
was the subject of a study that showed a marked improvement in
over 40% of the cases. Also observed were CCF due to congenital
anomaly of heart and valvular disease being brought under
control as well as 4 out of 9 cases of CCF as a result of
chronic bronchitis being relieved by the treatment. Symptomatic
complaints of essential hypertension viz. giddiness, insomnia,
lassitude, headache and a lack of concentration ability were
relieved by arjuna. Coagulation, bleeding and prothrombin time
can be reduced by oral administration of an aqueous suspension
of the bark powder.
References:
Phadnaik, B.S. and Parasar, G.C. 1981. Haematological studies on
Terminalia arjuna in respect of blood coagulation. Punjabrao
Krishi Vidyapeeth Res. J. 5, 1. Colabawala, H.M.
1951. An evaluation of the cardiotonic and other
properties of Terminalia arjuna. Indian Heart J. 3, 205-230.
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